A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 47/32 (2006.01)
Patent
CA 2669308
The invention relates to a transdermal therapeutic system which comprises a back layer that is impermeable to the active substance, and a peelable protective layer that is impermeable to the active substance and at least one matrix layer consisting of polysiloxanes and/or polysiloxane derivatives and containing micro-reservoirs. Said micro-reservoirs contain at least one ion pair from a pharmacologically active substance and an additive and either the active substance is nucleophilic and the additive is electrophilic or the active substance is electrophilic and the additive is nucleophilic.
Système thérapeutique transdermique comportant une couche arrière imperméable aux agents actifs, une couche protectrice pelable et imperméable aux agents actifs et au moins une couche matricielle composée de polysiloxanes et/ou de dérivés de polysiloxanes et comportant des microréservoirs qui contiennent au moins une paire d'ions formée par un agent pharmaceutiquement actif et par un additif, sachant que soit l'agent actif est nucléophile et l'additif est électrophile, soit l'agent actif est électrophile et l'additif est nucléophile.
Hille Thomas
Horstmann Michael
Mueller Walter
Fetherstonhaugh & Co.
Lts Lohmann Therapie-Systeme Ag
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