Tapentadol compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/192 (2006.01) A61K 31/197 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2706596

The present invention provides a method of treating pain and pain related conditions by administering to a patient in need thereof, a therapeutically effective amount of a slow release Tapentadol Hydrochloride and therapeutically effective amount of a second analgesic, wherein the second analgesic is tramadol, gamma- aminobutyric acid (GABA) analogue or an NSAID. The present invention further provides a pharmaceutical composition comprising a therapeutically effective amount of a slow release Tapentadol Hydrochloride and a therapeutically effective amount of a second analgesic, wherein the second analgesic is tramadol, gamma-aminobutyric acid (GABA) analogue or an NSAID.

La présente invention concerne un procédé de traitement de la douleur et de conditions liées à la douleur par administration à un patient le nécessitant d'une quantité thérapeutiquement efficace de chlorhydrate de tapentadol à libération lente et d'une quantité thérapeutiquement efficace d'un second analgésique, le second analgésique étant le tramadol, un analogue d'acide gamma-aminobutyrique (GABA) ou un AINS. La présente invention concerne en outre une composition pharmaceutique comprenant une quantité thérapeutiquement efficace de chlorhydrate de tapentadol à libération lente et une quantité thérapeutiquement efficace d'un second analgésique, le second analgésique étant le tramadol, un analogue d'acide gamma-aminobutyrique (GABA) ou un AINS.

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