Glucagon-like peptide-1 analogs

Details Glucagon-like peptide-1 analogs Glucagon-like peptide-1 analogs

C - Chemistry, Metallurgy

07

K

C07K 14/605 (2006.01) A61K 38/26 (2006.01) A61P 3/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2412004

Disclosed are glucagon-like peptide-1 (GLP-1) compounds with modifications at one or more of the following positions: 11, 12, 16, 22, 23, 24, 25, 27, 30, 33, 34, 35, 36, or 37. Methods of treating these GLP-1 compounds are also disclosed.

L'invention concerne des composés du type GLP-1 (glucagone-like peptide 1) présentant des modifications à au moins une des positions suivantes: 11, 12, 16, 22, 23, 24, 25, 27, 30, 33, 34, 35, 36 ou 37. L'invention concerne également des procédés permettant de traiter un sujet dont le récepteur de GLP-1 doit être stimulé, au moyen de ces composés du type GLP-1.

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