A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01)
Patent
CA 2576015
A method of treatment for treating, preventing, inhibiting or reducing damage to coronary tissue includes inducing at least one of a physiological function selected from: up-regulation of or increasing ILK activity in the coronary tissue, up-regulation of or increasing Akt activity in the coronary tissue, down-regulation of or reducing cardiomyocyte cell death in the coronary tissue and hibernation of cardiomyocytes in the coronary tissue. An induction agent capable of inducing such physiological function in a subject is administered to a subject in need of such treatment.
L'invention concerne une méthode de traitement permettant de traiter, de prévenir, d'inhiber ou de réduire les lésions causées au tissu coronaire, consistant à activer au moins une fonction physiologique choisie parmi les suivantes: régulation positive ou accroissement de l'activité Akt dans le tissu coronaire, régulation négative ou réduction de la mort des cardiomyocytes dans le tissu coronaire et de l'hibernation des cardiomyocytes dans le tissu coronaire. La méthode décrite consiste à administrer un agent activateur capable d'activer une telle fonction physiologique chez un sujet nécessitant un tel traitement.
Bock-Marquette Ildiko
Goldstein Allan L.
Saxena Ankor
Srivastava Deepak
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Regenerx Biopharmaceuticals Inc.
The Board Of Regents Of The University Of Texas System
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