C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) C07K 16/26 (2006.01) C12N 15/19 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2685594
The invention is related to isoforms of components of transcription factor complexes that are specifically expressed in cancer cells. These isoforms can be used as biomarkers for detection, diagnosis, prognosis and monitoring of treatments of cancer, and as drug targets of pharmaceutical compositions for the treatment of various cancers expressing the targeted isoforms. Methods, molecules, materials and kits for these uses are disclosed.
La présente invention concerne des isoformes de composants des complexes de facteurs de transcription qui sont spécifiquement exprimés dans les cellules cancéreuses. Ces isoformes peuvent être utilisés en tant que marqueurs biologiques pour la détection, le diagnostic, le pronostic et la surveillance de traitements anticancéreux et en tant que cibles pour des compositions pharmaceutiques destinées au traitement de divers cancers qui expriment les isoformes ciblés. L'invention concerne des procédés, des molécules, des substances et des kits destinés à ces utilisations.
Kazantseva Anna
Kazantseva Jekaterina
Oncotx Inc.
Sim & Mcburney
LandOfFree
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