Preparation of polyenes

Details Preparation of polyenes Preparation of polyenes

C - Chemistry, Metallurgy

07

C

C07C 403/00 (2006.01) C07C 1/32 (2006.01) C07C 11/21 (2006.01) C07C 45/60 (2006.01) C07C 47/21 (2006.01) C07D 319/06 (2006.01)

Patent

CA 2071772

O.Z. 0050/42562 Abstract of the Disclosure: An improved process for the preparation of polyenes by the Julia reaction comprises carrying out the allylation of the anion of an allyl aryl sulfone generated a strong base, and the elimination of arylsulfinic acid to form a double bond in the same inert polar solvent which is immiscible with water, preferably in a ketone of the formula I R1-CO-R2 (I) where R1 and R2 are each straight-chain or branched alkyl of 2 to 4 carbons, or R1 and R2 together are tetra- methylene or pentamethylene. The process is particularly important for the preparation of vitamin A derivatives. In the preparation of vitamin A aldehyde, for example, it is advantageous to use the same alkali metal alcoholate as strong base in both stages so that the conversion can be carried out as one-pot reaction.

Affiliated with

Also associated with

Rating

Preparation of polyenes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of polyenes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of polyenes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1867022