A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/18 (2006.01) A61K 9/14 (2006.01) A61K 47/02 (2006.01)
Patent
CA 2207599
A medicament adsorbate containing corn syrup having contained therein from about 10 to about 90 % by weight of the adsorbate of a medicament drug, a magnesium trisilicate having a surface area of at least 400 m2/g and having a structure with multiple interstitial spaces, and having adsorbed therein from about 0.5 to about 30 % by weight of the adsorbate of a medicament drug, wherein the medicament drug is an antihistamine. A reduction in the electrostatic forces between adsorbates is experienced due to the particle size of the adsorbate being in the range greater than 40 to about 800 um, most of the adsorbates prepared being a particle size greater than 150 um, which allows for better processing.
On décrit un adsorbsat médicamenteux contenant du sirop de maïs ayant contenu environ 10 à 90 % en poids d'adsorbat d'un médicament, un trisilicate de magnésium ayant une surface d'au moins 400 m?2¿/g et une structure contenant de multiples espaces interstitiels et ayant adsorbé environ 0,5 à 30 % en poids de l'adsorbat d'un médicament, ce dernier étant un antihistaminique. La réduction des forces électrostatiques entre les adsorbats s'effectue grâce à la taille des particules de l'adsorbat, qui se trouve dans la plage comprise entre plus de 40 et environ 800 mu, la plupart des adsorbats préparés ayant une taille de particules supérieure à 150 mu, ce qui permet un meilleur traitement.
Garay Felipe B.
Lech Stanley
Oehling Mark
Macrae & Co.
Warner-Lambert Company
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