Solid pharmaceutical composition containing a core and an...

Details Solid pharmaceutical composition containing a core and an... Solid pharmaceutical composition containing a core and an...

A - Human Necessities

61

K

167/166, 167/218

A61K 31/505 (2006.01) A61K 9/00 (2006.01) A61K 9/24 (2006.01)

Patent

CA 2020590

A solid pharmaceutical composition for release of a biologically active substance into a desired aqueous environment, containing a core and an outer layer, said core comprising between 17 and 93% by weight of the biologically active substance, between 0.01 and 7% by weight of a water swellable polymer material and between 0 and 83% of one or more accessory ingredients, relative to the total weight of the core; and the outer layer comprising between 25 and 75% by weight of the biologically active substance, between 25 and 75% by weight of a material for enabling rapid dispersion of the outer layer into the aqueous environment and 0 to 50% by weight of one or more accessory ingredients, relative to the total weight of the outer layer. The composition is preferably formulated as a bolus for veterinary use.

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