High dose radionuclide complexes for bone marrow suppression

Details High dose radionuclide complexes for bone marrow suppression High dose radionuclide complexes for bone marrow suppression

A - Human Necessities

61

K

A61K 51/04 (2006.01) A61K 47/22 (2006.01) A61P 19/00 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2371728

The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases, infectious diseases, metabolic diseases or genetic diseases, with compositions having as their active ingredient a radionuclide complexed with a chelating agent such as macrocyclic aminophosphonic acid.

La présente invention concerne un procédé de suppression de la moelle osseuse et de traitement des états qui apparaissent dans la moelle osseuse ou près d'elle tels que le cancer, les syndromes myéloprolifératifs, les maladies auto-immunes, les maladies infectieuses, les maladies métaboliques ou les maladies génétiques, le traitement se faisant au moyen de compositions dont le composant actif est un radionucléide formant un complexe avec agent chélateur tel que l'acide macrocyclique aminophosphonique.

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