Peptide compounds that bind her2

Details Peptide compounds that bind her2 Peptide compounds that bind her2

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/71 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/13 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2373721

The invention provides novel compounds which bind to the human erbB2 gene product (ErbB2, also known as HER2, or c-ErbB-2). In particular aspects, the invention provides for the treatment of disorders characterized by the overexpression of ErbB2 utilizing the novel compounds of the invention. The invention also provides pharmaceutical compositions comprising the novel compounds as well as for their use in research, diagnostic, therapeutic, and prophylactic methods.

L'invention concerne de nouveaux composés qui se lient au produit génique humain erbB2 (ErbB2, également appelé HER2, ou c-ErbB-2). Dans des aspects particuliers, l'invention concerne le traitement d'affections caractérisées par une surexpression d'ErbB2 au moyen des nouveaux composés de l'invention. L'invention concerne aussi des compositions pharmaceutiques contenant ces nouveaux composés, et leur utilisation dans des méthodes de recherche, diagnostiques, thérapeutiques et prophylactiques.

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