Purine derivatives having phosphodiesterase iv inhibition...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 473/18 (2006.01) A61K 31/52 (2006.01) A61K 31/522 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 31/18 (2006.01) A61P 37/08 (2006.01) C07D 473/20 (2006.01) C07D 473/22 (2006.01) C07D 473/24 (2006.01) C07D 473/34 (2006.01)

Patent

CA 2367143

Disclosed are compounds of formula (I), wherein R3, R6a, R6b and R8 are substituted as disclosed herein. The compounds are effective in effecting PDE IV inhibition in patients in need thereof.

L'invention concerne des composés représentés par la formule (I), dans laquelle R?3¿, R?6a¿, R?6b¿ et R?8¿ sont substitués de la manière décrite dans la demande. Les composés sont efficaces pour mettre en oeuvre un inhibition de PDE IV chez des patients nécessitant un tel traitement.

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