Benzazepine derivatives as monoamine reuptake inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 403/04 (2006.01) A61K 31/55 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2650147

Compounds of the formula (I); or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ar, R1 and R2 are defined herein. Also provided are pharmaceutical compositions, methods of preparing the compounds, and method of using the compounds for treatment of monoamine reuptake inhibitor-mediated diseases.

La présente invention concerne des composés de la formule (I) ; ou des sels, des solvates ou des promédicaments pharmaceutiquement acceptables de ceux-ci, où Ar, R1 et R2 sont définis dans le descriptif. Sont également proposées des compositions pharmaceutiques, des procédés pour préparer les composés, et des procédés pour les utiliser dans le traitement de maladies dont le médiateur est l'inhibiteur de la réabsorption de la monoamine.

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