Pyrazole or triazole compounds and their use for the...

A - Human Necessities – 61 – K

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Details

A61K 31/415 (2006.01) A61K 31/4152 (2006.01) A61K 31/4155 (2006.01) A61K 31/4162 (2006.01) A61K 31/4164 (2006.01) A61K 31/4192 (2006.01) A61K 31/433 (2006.01)

Patent

CA 2583971

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.

L'invention concerne des procédés, composés et compositions permettant de traiter ou prévenir des maladies associées à des mutations non-sens dans un ARNm, par administration de composés ou compositions de cette invention. Plus spécifiquement, l'invention concerne des procédés, composés et compositions permettant de supprimer la terminaison prématurée de traduction associée à une mutation non-sens dans un ARNm.

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