Use of eif-5a1 sirna to protect islets cells from apoptosis...

Details Use of eif-5a1 sirna to protect islets cells from apoptosis... Use of eif-5a1 sirna to protect islets cells from apoptosis...

C - Chemistry, Metallurgy

12

N

C12N 5/02 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) A61K 31/713 (2006.01)

Patent

CA 2700463

The present invention relates to methods for improving the viability, recovery and functionality of islets that are separated from a donor organ for subsequent transplantation and more particularly relates to the use of eIF-5A1 siRNAs to enhance the viability and functionality of islets.

La présente invention porte sur des procédés pour améliorer la viabilité, la récupération et la fonctionnalité d'îlots qui sont séparés d'un organe donneur pour une transplantation ultérieure et, plus particulièrement, porte sur l'utilisation d'ARNsi eIF-5A1 pour améliorer la viabilité et la fonctionnalité des îlots.

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