T cell induced tissue repair and regeneration

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61K 38/20 (2006.01) A61P 9/00 (2006.01) C12N 5/06 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2448591

The present invention relates to methods for the use of T cells or supernatants therefrom, and more particularly, activated T cells, in facilitating and/or regulating the differentiation, de-differentiation, maturation, organization, repair, and regeneration of various cells/tissues. Methods for inducing tissue repair and regeneration in vitro and in vivo are disclosed. The present invention also relates to compositions of cells, including activated T cells and/or cells resulting from the co-culture with activated T cells, and their use in inducing tissue repair and regeneration in vivo.

L'invention porte sur des procédés d'utilisation de cellules T ou de leurs surnageants et plus particulièrement de cellules T activées pour faciliter et/ou réguler la différentiation, de- différentiation, maturation, organisation, réparation et régénération de différentes ou cellules et tissus. L'invention porte également sur des procédés induisant la réparation et la régénération de tissus in vitro and in vivo, sur des compositions de cellules dont des cellules T activées et/ou des cellules résultant de co cultures avec des cellules T, et sur leur utilisation pour induire la réparation et la régénération de tissus in vivo.

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