G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/566 (2006.01)
Patent
CA 2609915
The instant invention is based, at least in part, on the discovery that T-bet controls ThI cell recruitment to sites of inflammation. This invention pertains to, inter alia, methods of identifying agents that modulate the effects of T-bet on the recruitment of T cells to sites of inflammation by modulating P-selectin-mediated T cell rolling and/or stable adherence of a T cell to a vascular endothelial cell, as well as methods of use therefore.
La présente invention est au moins en partie basée sur la découverte selon laquelle T-bet régule le recrutement de lymphocytes Th1 sur des sites d'inflammation. L'invention concerne, entre autres, des méthodes destinées à identifier des agents modulant les effets de T-bet sur le recrutement de lymphocytes T sur des sites d'inflammation par modulation du roulement des lymphocytes T médié par la P-sélectine et/ou de l'adhésion stable d'un lymphocyte T à une cellule endothéliale vasculaire, ainsi que des méthodes d'utilisation associées.
LandOfFree
Modulation of t cell recruitment does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Modulation of t cell recruitment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Modulation of t cell recruitment will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1871770