Anhydrous crystal of 4-carbamoyl-1-.beta.-d-ribofuranosyl...

Details Anhydrous crystal of 4-carbamoyl-1-.beta.-d-ribofuranosyl... Anhydrous crystal of 4-carbamoyl-1-.beta.-d-ribofuranosyl...

C - Chemistry, Metallurgy

07

H

260/229.8

C07H 19/052 (2006.01)

Patent

CA 2028416

Anhydrous crystals of 4-carbamoyl-I-.beta.-D-ribofuranosyl imidazolium-5-oleate are disclosed. The crystals possess (1) water content of 0.5% by weight or less (the Karl Fischer method), and (2) specific IR spectrum absorption peaks in the neighborhoods of 3580, 1852, 1630, 1575, and 1554 cm-1. They are stable against heat and high humidity conditions and can easily be manufactured by using ethanol. The compound has superior immuno-suppressing activity and is thus made into preparations for oral administration.

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