Ophthalmic formulations of cetirizine and methods of use

A - Human Necessities – 61 – K

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Details

A61K 31/495 (2006.01) A61P 27/02 (2006.01) A61P 27/14 (2006.01)

Patent

CA 2755679

The present invention provides stable topical formulations of cetirizine that provide a comfortable formulation when instilled in the eye and is effective in the treatment of allergic conjunctivitis and/or allergic conjunctivitis. The invention further provides methods of treating allergic conjunctivitis and/or allergic rhinoconjunctivitis in a subject in need of such treatment by topical application of the cetirizine formulations of the invention directly to the eye.

La présente invention concerne des formulations topiques stables de cétirizine qui fournissent une formulation confortable lorsqu'elles sont instillées dans l'il et qui sont efficaces dans le traitement de la conjonctivite allergique et/ou de la rhinoconjonctivite allergique. L'invention concerne en outre des procédés de traitement de la conjonctivite allergique et/ou de la rhinoconjonctivite allergique chez un sujet nécessitant un tel traitement par application topique de formulations de cétirizine de l'invention directement dans l'il.

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