G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/564 (2006.01) C40B 30/04 (2006.01) C07K 14/35 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2616766
Serum antibody assays capable of distinguishing cases of inactive TB from cases of active TB include a combination at least three M. tuberculosis protein antigens, at least one for which a positive response is consistent with inactive TB and antigens, and at least one for which a negative response is consistent with inactive TB. Preferred assays further distinguish other TB classes. Also, antigen kits for performing such assays.
La présente invention concerne des dosages d'anticorps sériques capables de distinguer des cas de tuberculose inactive de cas de tuberculose active, lesquels dosages comprennent une combinaison d'au moins trois antigènes des protéines de M tuberculosis dont au moins un présente une réponse positive compatible avec la tuberculose inactive et les antigènes et dont au moins un présente une réponse négative compatible avec la tuberculose inactive. Des dosages préférés distinguent également d'autres catégories de tuberculose. Cette invention concerne également des trousses d'antigènes permettant d'effectuer ces dosages.
Dimock Stratton Llp
University Of Medicine And Dentistry Of New Jersey
LandOfFree
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