B - Operations – Transporting – 65 – D
Patent
B - Operations, Transporting
65
D
B65D 77/20 (2006.01) A61J 1/00 (2006.01) B65D 83/04 (2006.01) A61K 9/14 (2006.01) A61K 31/7048 (2006.01) A61M 15/00 (2006.01)
Patent
CA 2623256
A receptacle (100) includes a holder (5) forming a cavity (25) that holds a pharmaceutical (110) , a lid (15) , and adhesive (17) that forms a bond (20) between the holder (5) and the lid (15) . As an example, the bond (20) has a shape that includes a protrusion (30) that facilitates removal of the lid (15) from the holder (5) . A kit (60) includes a plurality of containers containing powder including amphotericin B and pharmaceutically acceptable excipient. The kit (60) also includes an aerosolization apparatus (1100) and instructions. As an example, the pharmaceutical composition is made from particles including amphotericin B having a mass median diameter less than about 3 µm, such as from about 1.1 µm to about 1.9 µm.
L'invention concerne un récipient comprenant un élément de confinement définissant une cavité pour le confinement d'un agent pharmaceutique, un couvercle et un adhésif formant une liaison entre l'élément de confinement et le couvercle. Par exemple, la liaison présente une forme comprenant une saillie facilitant la séparation du couvercle de l'élément de confinement. Une trousse comprend une pluralité de récipients contenant une poudre renfermant de l'amphotéricine B et un excipient pharmaceutiquement acceptable. La trousse comprend également un appareil d'aérosolisation et des instructions. Par exemple, la composition pharmaceutique est constituée de particules renfermant de l'amphotéricine B présentant une diamètre moyen en masse inférieur à environ 3 µm, et notamment compris entre environ 1,1 µm et environ 1,9 µm.
Chan Leo
Cheu Scot
Gowling Lafleur Henderson Llp
Nektar Therapeutics
Novartis Ag
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