Aptamer inhibitors of osteopontin and methods of use thereof

Details Aptamer inhibitors of osteopontin and methods of use thereof Aptamer inhibitors of osteopontin and methods of use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01) A61K 48/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2714535

The present invention polynucleotide aptamers that selectively bind to and in-hibit the function of osteopontin, pharmaceutical compositions comprising the same, and meth-ods of use for diagnostics and treatment of diseases and disorders associated with osteopontin.

Cette invention concerne des aptamères polynucléotidiques qui se lient sélectivement à et inhibent la fonction de lostéopontine, des compositions pharmaceutiques comprenant ces aptamères et leurs procédés dutilisation pour le diagnostic et le traitement de maladies et daffections associées avec lostéopontine.

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