Quinazolinone derivatives useful as vanilloid antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 239/91 (2006.01) A61K 31/517 (2006.01)

Patent

CA 2567821

The present invention relates to the use of a quinazolinone compound of the formula (I) wherein R1, R2, R3, R4, R5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form, as a vanilloid.

L'invention porte sur l'utilisation d'un composé de la quinazolinone, de formule (I) dans laquelle: R¿1?, R¿2?, R¿3?, R¿4?, R¿5? et m sont tels que définis dans la spécification et dans les revendications, sous forme libre ou de sels et quand cela est possible sous forme de sels acidifiants, et s'utilisant en tant qu'antagonistes du vanilloïde.

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