A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01)
Patent
CA 2607214
Compositions having a plasmid containing a polynucleotide encoding an autoantigen or a donor antigen and a polynucleotide encoding a pro-apoptotic protein, or two separate plasmids encoding the same, for preventing, delaying the onset of or treating an immune- mediated inflammatory disorder are disclosed. At least one of the plasmids having methylated GpG motifs. Also disclosed is the combined use of a plasmid encoding the secreted form of glutamic acid decarbozylase 55 (SGAD55) and a plasmid encoding the proapoptotic protein Bax in treating type 1 diabetes, wherein the plasmid encoding SGAD55 is methylated at CpG motifs.
L'invention concerne une matière ou une composition destinée à prévenir ou à traiter un ou plusieurs troubles inflammatoires à médiation immune, ou à retarder le déclenchement de celui/ceux-ci dans un organisme susceptible de développer, en train de développer ou présentant ce(s) trouble(s) inflammatoire(s). Elle concerne aussi un procédé visant à prévenir ou à traiter un organisme susceptible de développer, en train de développer ou présentant ce(s) trouble(s) inflammatoire(s), ou à en retarder le déclenchement.
Escher Alan P.
Li Fengchun
Gowling Lafleur Henderson Llp
Loma Linda University
LandOfFree
Substances, compositions and methods for preventing and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substances, compositions and methods for preventing and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substances, compositions and methods for preventing and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1875875