Substituted piperidines as therapeutic compounds

Details Substituted piperidines as therapeutic compounds Substituted piperidines as therapeutic compounds

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/5377 (2006.01) A61P 25/28 (2006.01) A61P 31/18 (2006.01) A61P 33/06 (2006.01)

Patent

CA 2719070

Described are compounds of the general formula (I), and pharmaceutically acceptable salt thereof, in which R1 has the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibitors.

Cette invention concerne des composés de formule générale (I), et des sels pharmaceutiquement acceptables de ceux-ci. Dans la formule (I), R1 a les définitions indiquées en détail dans la description. Les composés selon l'invention peuvent être utilisés à titre d'inhibiteurs de bêta-sécrétase, de cathepsine D, de plasmepsine II et/ou de protéase du VIH.

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