Method for the inhibition of cell-cell and cell-substratum...

A - Human Necessities – 61 – K

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A61K 39/00 (2006.01) A61K 31/70 (2006.01) A61K 38/02 (2006.01)

Patent

CA 2008519

37 METHODS FOR THE INHIBITION OF CELL-CELL AND CELL-SUBSTRATUM INTERACTIONS BY THE BLOCKING OF CARBOHYDRATE-CARBOHYDRATE INTERACTIONS Abstract of the Disclosure Methods for the inhibition of cell-cell and cell- substratum interactions by the blocking of carbohydrate- carbohydrate interactions are disclosed. Inhibition of cell- cell and cell-substratum interactions by the methods of the present invention permit the inhibition of a variety of biological phenomena, including metastases, mammalian diseases that are microbial in origin, mammalian fertilization, and plant pathologies. Suitable agents for blocking carbohydrate- carbohydrate interactions include saccharides, glycocon- jugates, and antibodies directed against carbohydrate determinants. WD10-19/1536402E/V2

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