Combination comprising docetaxel and a cdk inhibitor

A - Human Necessities – 61 – K

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Details

A61K 31/337 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2502973

A first aspect of the invention relates to a combination comprising docetaxel, or a derivative or prodrug thereof, and a CDK inhibitor. A second aspect of the invention relates to a pharmaceutical product comprising docetaxel, or a derivative or prodrug thereof, and a CDK inhibitor as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method of treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering a docetaxel, or a derivative or prodrug thereof, and a CDK inhibitor to a subject.

Dans un premier mode de réalisation l'invention concerne une combinaison contenant du docétaxel, ou un dérivé ou un promédicament de ce produit, et un inhibiteur de CDK. Dans un deuxième mode de réalisation, l'invention concerne un produit pharmaceutique comprenant du docétaxel, ou un dérivé ou un promédicament de ce produit, et un inhibiteur de CDK entant que préparation combinée d'utilisation simultanée, séquentielle ou séparée en thérapie. Dans un troisième mode de réalisation, l'invention concerne un procédé de traitement d'un trouble prolifératif, ce procédé consistant à administrer simultanément, séquentiellement ou séparément du docétaxel, ou un dérivé ou un promédicament de ce produit, et un inhibiteur de CDK à un sujet.

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