Formulations of haloalkylamines and local anaesthetics and...

Details Formulations of haloalkylamines and local anaesthetics and... Formulations of haloalkylamines and local anaesthetics and...

A - Human Necessities

61

K

A61K 31/46 (2006.01) A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 31/155 (2006.01) A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/24 (2006.01) A61K 31/245 (2006.01) A61K 31/445 (2006.01) A61K 31/47 (2006.01) A61K 31/535 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2230648

The present invention pertains to the field of pain management in medicine. Methods for treating reflex sympathetic dystrophy (including causalgia) are provided, in which a haloalkylamine .alpha. adrenergic blocking agent and a local anaesthetic are administered to the affected limb by intravenous regional block. Formulations which can be used in these methods are also provided. In a preferred embodiment, phenoxybenzamine and either lidocaine or procaine are administered to the affected limb using a Bier block procedure.

Dans le domaine du traitement de la douleur en médecine, la présente invention porte sur des méthodes de traitement de la distrophie sympathique réflexe (y compris de la causalgie), selon lesquelles un agent alphabloquant alkylamine halogéné et un anesthésiant local sont administrés au membre lésé par anesthésie régionale intraveineuse. L'invention porte aussi sur les formulations pouvant être utilisées dans le cadre de ces méthodes. Selon le mode de réalisation préféré, on administre de la phénoxybenzamine et soit de la lidocaïne soit de la procaïne au membre lésé par anesthésie locale intraveineuse.

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