Human dnase ii

Details Human dnase ii Human dnase ii

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) A61K 38/46 (2006.01) C07K 16/40 (2006.01) C12N 9/16 (2006.01) C12N 9/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2250433

This invention relates to a novel human deoxyribonuclease, referred to as human DNase II. The invention provides nucleic acid sequences encoding human DNase II, thereby enabling the production of human DNase II by recombinant DNA methods in quantities sufficient for clinical use. The invention also relates to pharmaceutical compositions and diagnostic and therapeutic uses of human DNase II.

L'invention concerne une nouvelle désoxyribonucléase humaine, désignée par DNase II humaine. Elle se rapporte également à des séquences nucléotidiques codant la DNase II humaine, et permettant ainsi la production de DNase II humaine par des méthodes de recombinaison de l'ADN à des fins cliniques. L'invention porte également sur des compositions pharmaceutiques et des utilisations diagnostiques et thérapeutiques de la DNase II humaine.

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