Process for producing 13-cis retinoic acid

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 403/20 (2006.01) C07C 51/353 (2006.01) C07B 61/00 (2006.01)

Patent

CA 2325517

The process of the present invention relates to a process for producing 13-cis retinoic acid. The process of the present invention involves reacting a Wittig salt in a solvent with a butenolide in the presence of a weak base and optionally, a Lewis acid.

La présente invention concerne un procédé permettant la production d'acide 13-cis rétinoïque. Ce procédé consiste à prendre un sel de Wittig dans un solvant et à le faire réagir avec un buténoïde en présence d'une base faible et éventuellement d'un acide de Lewis.

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