1-(2-naphthyl) and...

Details 1-(2-naphthyl) and... 1-(2-naphthyl) and...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) C07D 215/38 (2006.01) C07D 239/84 (2006.01) C07D 241/44 (2006.01) C07D 295/02 (2006.01) C07D 295/073 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2308057

Disclosed are compounds of formula: (I) or pharmaceutically acceptable addition salts thereof, wherein: X, Y and Z are the same or different and represent optionally substituted carbon or nitrogen; R1 and R2 independently represent organic or inorganic substituents; R3 and R4 are variables independently representing inorganic or organic substituents; A represents C1- C4 alkylene; and R5, R6 and R7 independently represent hydrogen or C1-C6 alkyl, which compounds bind selectively with high affinity to the dopamine D4 receptor subtype and are therefore of use in treatment of various neuropsychological disorders.

On décrit des composés de la formule (I) ou des sels d'addition pharmaceutiquement acceptables desdits composés. Dans ladite formule, X, Y et Z sont identiques ou différents et représentent carbone ou azote éventuellement substitués; R¿1? et R¿2? sont, indépendamment, des substituants organiques ou inorganiques; R¿3? et R¿4? sont des variables représentant, indépendamment, des substituants organiques ou inorganiques; A est alkylène C¿1?-C¿4?; et R¿5?, R¿6? et R¿7? sont, indépendamment, hydrogène ou alkyle C¿1?-C¿6?. Lesdits composés se lient sélectivement au sous-type du récepteur D¿4? de la dopamine pour lequel ils ont une grande affinité, et conviennent donc pour le traitement de divers troubles neuropsychologiques.

Affiliated with

Also associated with

Rating

1-(2-naphthyl) and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-(2-naphthyl) and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-(2-naphthyl) and... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1880576