Therapeutic antennapedia-antibody molecules and methods of...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/00 (2006.01) C07K 16/44 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2758378

An antibody or fragment thereof combined with Antennapedia or a fragment thereof, is an effective therapeutic agent. The invention describes the construction of antibody or antibody fragment fused or chemically conjugated with Antennapedia at its carboxyl or its amino terminus (a "cargo-carrier" construct).

L'invention porte sur un anticorps ou un fragment de celui-ci combiné avec antennapedia ou un fragment de celle-ci, qui est un agent thérapeutique efficace. L'invention décrit la construction de l'anticorps ou du fragment d'anticorps fusionné ou chimiquement conjugué avec antennapedia à son extrémité carboxyle ou amino (un produit de construction « transport de charge »).

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