Use of nitric oxide-releasing agents for reducing metastasis...

Details Use of nitric oxide-releasing agents for reducing metastasis... Use of nitric oxide-releasing agents for reducing metastasis...

A - Human Necessities

61

K

A61K 31/13 (2006.01) A61K 31/14 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2205555

A method for inhibiting the adherence between cancerous cells and noncancerous structures in a mammal, comprising the administration to the mammal of a nitric oxide-releasing compound containing a nitric oxide-releasing N2O2- functional group. The compound is capable of releasing an adherence-inhibiting effective amount of nitric oxide to the mammal.

La présente invention concerne un procédé destiné à réduire chez un mammifère l'adhérence entre cellules cancéreuses et structures non cancéreuses. Le procédé consiste en l'administration au mammifère d'un composé libérant de l'oxyde nitrique car contenant un groupe fonctionnel N¿2?O¿2??-¿ libérant de l'oxyde nitrique. Ce composé est capable de libérer chez le mammifère une quantité d'oxyde nitrique suffisante pour bloquer le phénomène d'adhérence.

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