C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/55 (2006.01) A61P 25/28 (2006.01) C07D 223/12 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2595173
The invention provides N-substituted heterocyclic-sulfonamides for use in treating or preventing cognitive disorders, such as Alzheimer's Disease. Compounds of particular interest are defined by Formula (I), wherein R1, R2, Z and n are as described in the specification. The invention also encompasses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of treating cognitive disorders using compounds of Formula (I).
L'invention concerne des sulfamides hétérocycliques N-substitués à utiliser dans le traitement ou la prévention de troubles cognitifs, de type maladie d'Alzheimer. L'invention concerne des composés d'intérêt particulier définis par la formule (I), dans laquelle R1, R2, Z et n ont la signification indiquée dans la description. L'invention concerne également des compositions pharmaceutiques comprenant les composés de formule (I) ainsi que des procédés de traitement de troubles cognitifs faisant intervenir des composés de formule (I).
Elan Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
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