Medium-chain length fatty acids, glycerides and analogues as...

A - Human Necessities – 61 – K

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A61K 31/20 (2006.01)

Patent

CA 2515160

Use of a composition comprising a compound of any of formulae I, II, Ila, III and Illa; or a combination thereof wherein each R1 is independently C7-11 alkyl; A and B are independently H or CO-R1; R2 is H or C1-4 alkyl; M is a metal monocation (k = 1) or dication (k = 2); Y is 0 or NH; and Z is 0, NH, CH2O or a bond; for the manufacture of a medicament for stimulating erythropoiesis. Preferably, the composition further comprises human erythroporietin.

L'invention concerne l'utilisation d'une composition comprenant un composé représenté par la formule I, II, Ila, III ou IIIa; ou une combinaison de celles-ci, dans lesquelles chaque R¿1? représente indépendamment alkyle C¿7-11?; A et B représentent indépendamment H ou CO-R¿1?; R¿2? représente H ou alkyle C¿1-4?; M représente un monocation (k=1) ou un dication (k=2) métallique ; Y vaut 0 ou NH; et Z vaut 0, NH, CH¿2?O ou une liaison; pour la fabrication d'un médicament pour la stimulation de l'érythropoïèse. La composition comprend de préférence de l'érythropoïétine humaine.

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