C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/40 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 25/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2504350
The present invention establishes a link between altered aPKC function and nervous system disorders and cancers, such as Alzheimer's disease (AD) and neuroblastoma. Methods of using aPKC in diagnosis, drug screening and gene therapy in nervous system disorders and cancers are provided.
La présente invention établit un lien entre une fonction aPKC (protéine kinase C atypique modifiée) et des troubles du système nerveux ainsi que des cancers, tels que la maladie d'Alzheimer (AD) et le neuroblastome. Sont prévus des procédés d'utilisation d'une aPKC en diagnostic, dans le criblage de médicaments et en thérapie génique dans des troubles du système nerveux et dans les cancers.
Crary John Fonda
Hernandez Alejandro Ivan
Mirra Suzanne
Sacktor Todd C.
Shao Charles
Crary John Fonda
Hernandez Alejandro Ivan
Mcfadden Fincham
Mirra Suzanne
Sacktor Todd C.
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