1,3,4-substituted piperidine analogs and uses thereof in...

C - Chemistry – Metallurgy – 07 – D

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C07D 211/60 (2006.01) A61K 31/451 (2006.01) A61K 31/454 (2006.01) A61P 25/36 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2395075

One aspect of the present invention relates to piperidine compounds and pharmaceutical compositions thereof. A second aspect of the present invention relates to the use of piperidine compounds and pharmaceutical compositions thereof as promoters of 5-HT2A antagonistic activity. A third aspect of the invention relates to methods of treating addiction using a compound of the invention or pharmaceutical compositions thereof.

L'invention concerne, dans un aspect, des composés d'alkylpipéridine et des compositions pharmaceutiques obtenues à partir desdits composés. Elle concerne, dans un deuxième aspect, l'utilisation de composés d'alkylpipéridine et de compositions pharmaceutiques obtenues à partir desdits composés comme promoteurs d'activité antagoniste au récepteur de 5-HT¿2A?. Dans un troisième aspect, l'invention concerne des méthodes de traitement de la toxicomanie mettant en oeuvre un composé de l'invention ou des compositions pharmaceutiques obtenues à partir dudit composé.

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