Invert emulsion type composition containing at least one...

Details Invert emulsion type composition containing at least one... Invert emulsion type composition containing at least one...

A - Human Necessities

61

K

A61K 47/24 (2006.01) A61K 9/113 (2006.01)

Patent

CA 2514558

The present invention relates to a composition containing at least one active agent sensitive to the presence of water, characterized in that the composition is an invert emulsion containing a glycolic or hydroglycolic dispersed hydrophilic phase, a lipophilic continuous phase and an emulsifier having an HLB of between 2 and 7. This invert emulsion makes it possible to avoid the crystallization of the active agent and/or its chemical degradation, while having good stability and being well tolerated.

L'invention concerne une composition contenant au moins un agent actif sensible à la présence d'eau, caractérisée en ce que ladite composition est une émulsion inverse contenant une phase hydrophile, dispersée glycolique ou hydroglycolique, une phase continue lipophile et un émulsifiant présentant un rapport hydrophile-lipophile compris entre 2 et 7. L'émulsion inverse permet d'éviter la cristallisation de l'agent actif et/ou sa dégradation chimique, tout en conservant une bonne stabilité et en étant bien tolérée.

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