A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/27 (2006.01) A61K 38/18 (2006.01) A61K 47/32 (2006.01) A61K 9/00 (2006.01) A61K 9/70 (2006.01)
Patent
CA 2368364
The present invention relates to a stable composition which comprises an epidermal growth factor (hereinafter referred to as "EGF") as an active ingredient and a carboxyvinyl polymer as a base. The present inventors have identified that the EGF preparation comprising EGF as an active ingredient and acidic polymer such as carboxyvinyl polymer as a base has significant stability as compared with the prior arts using the base such as cellulose based polymer or neutral polymer. Therefore, the composition according to the present invention is useful in eye formulations, topical formulations for the skin and cosmetic formulations and so on.
L'invention se rapporte à une composition stable qui comporte comme principe actif un facteur de croissance épidermique (désigné ci-après par l'acronyme "EGF") et comme base un carboxy polymère. Cette préparation à base d'EGF, qui comporte en tant que principe actif un EGF et en tant que base un polymère acide tel qu'un polymère de carboxyvinyle, présente une stabilité importante en comparaison des préparations antérieures dont la base était un polymère à base de cellulose ou un polymère neutre. Cette composition s'avère par conséquent utile dans les formulations oculaires, les formulations topiques à usage cutané et les formulations cosmétiques et analogues.
Kim Young-Jun
Lee Jang-Won
Shon Mi-Young
Yang Jeong-Hwa
Daewoong Pharm. Co. Ltd.
Robic
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