Methods for generating high titer helper-free preparations...

Details Methods for generating high titer helper-free preparations... Methods for generating high titer helper-free preparations...

C - Chemistry, Metallurgy

12

N

C12N 7/02 (2006.01) C07K 14/015 (2006.01) C12N 5/10 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2342849

The invention described herein provides methods of producing rAAV particles by culturing producer cells under conditions, such as temperature and pH, that promote release of virus.

L'invention concerne des procédés de production de particules d'AAVr au moyen d'une culture de cellules productrices dans des conditions de température et de pH qui provoquent la libération d'un virus.

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