A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 47/06 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01)
Patent
CA 2624050
Present proposals for liquid-medium carriers for glass particles comprising pharmaceutical compositions have had problems associated with aggregation of the glass particles. This has been previously solved by matching the density of the particles and a liquid in which they are suspended. However, though this greatly constrains the choice of liquid carrier that can be used. An alternative solution to this problem has been found. By adding just a small amount of liquid (2) to the particles (1), a flowable mixture is formed of a creamy or paste-like consistency. Providing too much liquid (2) is not present, the particles (1) do not separate out and so the choice of liquid carriers available for use in compositions of this type is greatly increased.
L'invention concerne des supports pour milieux liquides comprenant des compositions pharmaceutiques qui présentent des problèmes associés à l'agrégation de particules à base de verre. Ces problèmes ont été antérieurement résolus par mise en correspondance des densités des particules et du liquide dans lequel elles étaient suspendues. Toutefois, bien que ceci soit une grande contrainte, on peut choisir le support de liquide pouvant être utilisé. On a trouvé une solution alternative à ce problème uniquement par adjonction d'une petite quantité de liquide (2) aux particules (1), ce qui permet de former un mélange fluide de consistance crémeuse ou pâteuse. Lorsqu'on ne fournit par suffisamment de liquide (2), les particules (1) ne se séparent pas et le choix des supports liquides disponibles à utiliser dans les compositions de ce type est grandement augmenté.
Cambridge Biostability Limited
Fetherstonhaugh & Co.
Nova Bio-Pharma Technologies Limited
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