Pharmaceutical uses of nab1 and nab2

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2336805

The invention relates to the use, particularly in gene therapy, of an NAB1 or NAB2 polypeptide or a biologically active fragment thereof, and to nucleic acid molecules encoding such polypeptides, in the manufacture of a medicament for the treatment of cell proliferation disorders associated with wound healing in a mammal, including human.

La présente invention concerne l'utilisation, en particulier en thérapie génique, d'un polypeptide ou d'un fragment biologiquement actif de NAB1 ou de NAB2, et des molécules d'acides nucléiques qui codent pour de tels polypeptides, dans la fabrication d'un médicament destiné au traitement des troubles de la prolifération cellulaire associés à une cicatrisation chez un mammifère, y compris chez l'homme.

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