A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/44 (2006.01) C12N 5/073 (2010.01) A61K 35/14 (2006.01) C12N 5/0789 (2010.01) A61M 5/14 (2006.01)
Patent
CA 2703428
A pharmaceutical composition comprising hematopoietic stem cells isolated from pooled umbilical cord blood from separate donors, which can be infused in a patient in need of an umbilical cord blood transplant to increase the speed and success of engraftment. A method and a pooling criteria for minimizing lysis of total nucleated cells in pooled umbilical cord blood from separate donors is also provided. The method involves considering the ABO blood types of the donors of the umbilical cord blood units to be pooled as well as the ABO blood type of the respective mothers. The present invention also provides a means for increasing the availability of cord blood transplants to adults or individuals greater than 65 or 70 kilograms.
Laneuville Pierre
Peltier Linda
Goudreau Gage Dubuc
Mcgill University Health Center
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