Preparation of substituted isoserine esters using metal...

Details Preparation of substituted isoserine esters using metal... Preparation of substituted isoserine esters using metal...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) C07D 205/08 (2006.01) C07D 403/00 (2006.01) C07F 7/08 (2006.01) C07F 9/568 (2006.01)

Patent

CA 2254273

This application provides an alkoxide of the formula: Image where, for example, M is a metal; R15 is hydrogen; R16 is a lower alkanoyloxy group; R17 and R18 form an oxo group; R19 is hydrogen; R20 is a lower alkanoyloxy group; R21 is a hydrogen group; R22 and R23 form an oxetane ring; R24 is a lower alkanoyloxy group; R25 is an aryloyloxy group; R26 is a hydrogen group; and R27 is a hydroxy group. The invention also provides a .beta.-lactam of the formula: Image where, for example, R1 is an alkoxy group, R2 is hydrogen, R3 is hydrogen, R4 is an alkyl group, and R5 is a -COOR10 group, where R10 is an alkyl group.

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