Analysis of dna

Details Analysis of dna Analysis of dna

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2100790

2100790 9213100 PCTABS00014 A method is disclosed of recovering from two mixtures of DNA those sequences which are present in both mixtures (coincident sequences). DNA in a first mixture is produced in single stranded form to which are annealed capture oligonucleotides with known sequences. The first mixture is combined with single stranded DNA in a second mixture. Sequences in the second mixture anneal to homologous sequences in the first mixture. "Captured" homologous sequences are ligated to the capture oligonucleotides and heteroduplex coincident DNA sequences are then recovered.

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