Sulfonamides, sulfamates and sulfamides as gamma-secretase...

Details Sulfonamides, sulfamates and sulfamides as gamma-secretase... Sulfonamides, sulfamates and sulfamides as gamma-secretase...

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) A61K 31/415 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/454 (2006.01) A61P 25/28 (2006.01) C07D 231/12 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2503868

Compounds of formula I inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.

La présente invention concerne des composés représentés par la formule (I) et inhibant le traitement de la protéine précurseur de l'amyloïde ou "APP" (Amyloid Precursor Protein) par les gamma-secrétases. Ces composés conviennent donc au traitement ou à la prévention de la maladie d'Alzheimer.

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