Pyridazine compounds, their production and use

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/50 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 471/14 (2006.01) C07D 487/14 (2006.01) C07D 491/147 (2006.01) C07D 495/14 (2006.01)

Patent

CA 2086164

Pyridazine Compounds, Their Production and Use ABSTRACT OF THE DISCLOSURE Novel compound represented by the formula: Image wherein X stands for a methine group or a nitrogen atom; R1 stands for a hydrogen atom, an optionally substituted lower alkyl group or a halogen atom; R2 and R3 respectively stand for a hydrogen atom or an optionally substituted lower alkyl group, or, taken together, may form a 5- to 7 membered ring combined with the adjacent -C=C-; R4 and R5 respectively stands for a hydrogen atom or an optionally substituted lower alkyl group or, taken together, form a 3- to 7-membered homo- or hetero-cyclic ring combined with the adjacent carbon atom; A stands for an optionally substituted amino group; m and n denote 1 to 4, respectively, or salts thereof which has an antiallergic, antiinflammatory and anti-PAF activity and is useful as an antiasthmatic agent.

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