New use of substituted quinoline carboxamide

Details New use of substituted quinoline carboxamide New use of substituted quinoline carboxamide

Category

A - Human Necessities

Subcategory

61

Subsubcategory

K

IPC codes

A61K 31/47 (2006.01)

Type

Patent

Patent number

CA 2120712

Description

2120712 9306829 PCTABS00021 The use of an anti-MS quinoline-3-carboxamide compound comprising the structure of formula (I), optionally with substituents for the H1-9 hydrogen, or a salt of said compound where (a) ------------- represents that there are two conjugated double bonds between atoms comprised by the dashed line (only formula I), (b) the hydrogens H7 and H8 are attached to different atoms selected from X1, X2 and the nitrogen atom in the quinoline ring, (c) X1 and X2 are independently selected from an oxygen atom or an NH9 group, said X1 and X2 being bound by a single bond to the ring when carrying H7 or H8 and by a double bond when not carrying H7 or H8, for the manufacture of a composition intended for the treatment of conditions associated with MS. Also described are treatment regimens for MS patients. The particularly preferred compound is roquinimex or a salt thereof.

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