Synthesis of glycopolymers

Details Synthesis of glycopolymers Synthesis of glycopolymers

C - Chemistry, Metallurgy

12

P

C12P 19/28 (2006.01) C07H 3/06 (2006.01) C07H 15/04 (2006.01) C08B 37/00 (2006.01) C12P 19/04 (2006.01) C12P 19/14 (2006.01)

Patent

CA 2217741

Neoglycoconjugates and new intermediates for the synthesis thereof are synthesized by use of Endo-.beta.-<u>N</u>-acetylglucosaminidase from Arthrobacter protophormiae (Endo-A) in a medium containing organic solvent. Such methods allow for the synthesis of novel glycoconjugates including high mannose glycopolymers.

L'invention concerne des composés néoglycoconjugués et de nouveaux intermédiaires pour leur synthèse, par l'utilisation d'une endo-.beta.-<u>N</u>-acétylglucosaminidase d'Arthrobacter protophormiae (Endo-A) dans un milieu contenant un solvant organique. Ces procédés permettent la synthèse de nouveaux composés glycoconjugués, en particulier des glycopolymères à haute teneur en mannose.

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