Semicarbazide derivatives and the use thereof as...

Details Semicarbazide derivatives and the use thereof as... Semicarbazide derivatives and the use thereof as...

C - Chemistry, Metallurgy

07

C

C07C 317/42 (2006.01) A61K 31/175 (2006.01) A61K 31/18 (2006.01) A61K 31/195 (2006.01) A61K 31/4245 (2006.01) A61P 7/02 (2006.01) A61P 9/08 (2006.01) A61P 9/10 (2006.01) A61P 25/06 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 43/00 (2006.01) C07C 281/06 (2006.01) C07C 311/47 (2006.01) C07C 317/40 (2006.01) C07D 271/06 (2006.01)

Patent

CA 2478528

The invention relates to the novel compounds of formula (I), wherein R, R1, R2 and R3 are defined as in claim 1. The novel compounds are inhibitors of coagulation factor Xa and are used in the prophylaxis and/or therapy of thromboembolic diseases and in the treatment of tumors.

L'invention concerne de nouveaux composés de formule (I) dans laquelle R, R?1¿, R?2¿ et R?3¿ ont la signification indiquée dans la première revendication. Ces composés constituent des inhibiteurs du facteur de coagulation Xa et peuvent être utilisés pour prévenir et/ou traiter des maladies thromboemboliques ainsi que pour traiter des tumeurs.

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