Synthesis of sphingosines

Details Synthesis of sphingosines Synthesis of sphingosines

C - Chemistry, Metallurgy

07

C

C07C 215/24 (2006.01) C07C 213/02 (2006.01)

Patent

CA 2174431

Provided by the present invention is a process for the biocatalytic synthesis of optically pure sphingosines from achiral starting material. The stereoisomers of sphingosine are prepared from chiral arene diols using stereospecific reaction techniques to obtain the desired sphingosine or derivative thereof.

L'invention concerne un procédé de synthèse biocatalytique de sphingosines optiquement pures à partir d'un produit de départ achiral. On prépare des stéréoisomères de sphingosine à partir de diols d'arène chiraux en utilisant des techniques de mise en réaction stérospécifiques de manière à obtenir ladite sphingosine désirée ou un dérivé de celle-ci.

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